Course

Course Summary
Credit Type:
Course
ACE ID:
OOSL-0114
Organization's ID:
CHEM450
Organization:
StraighterLine
Location:
Online
Length:
14 weeks (75 hours)
Dates Offered:
Credit Recommendation & Competencies
Level Credits (SH) Subject
Upper-Division Baccalaureate 4 Survey of Biochemistry
Description

Objective:

Upon the successful completion of this course, students will be able to study the laws of chemical reactions at a molecular level to better understand the biological world. Students will study how structure affects function in water, amino acids, peptides, proteins, enzymes, carbohydrates, nucleotides, nucleic acids, and lipids. They will study the processes and regulation of processes through glycolysis, fatty acid catabolism, the citric acid cycle, lipid biosynthesis and hormonal regulation. Finally, students will learn how the structure and function of genes, chromosomes, DNA, RNA, and other proteins affect metabolism.

Learning Outcomes:

  • Identify weak interactions in aqueous systems, ionizations of water, and buffers against pH changes in biological systems.
  • Contrast primary, secondary, tertiary, and quaternary structures of proteins and their effects on binding and interactions.
  • Sort monosaccharides, disaccharides, polysaccharides, and glycoconjugates.
  • Understand nucleic acid structure and chemistry.
  • Contrast the functions and features of lipids when acting as signals, cofactors, and pigments.
  • Understand the relationship of membrane dynamics with their composition and architecture.
  • Explain how the G Protein, gated ion channels, regulation of transcription and cell cycle achieve biochemical signaling.
  • Identify the effects of bioenergetics and thermodynamics on metabolism.
  • Explain the role of glycogen and glycolysis in metabolic pathways.
  • Articulate the citric acid cycle.
  • Understand the digestion, mobilization, and transport of fats.
  • Articulate the role of ATP in oxidative phosphorylation.
  • Explain the biosynthesis of fatty acids, triacylglycerols and membrane phospholipids.
  • Understand the role of hormone regulation on metabolism.
  • Articulate how genes, chromosomes, DNA, RNA, and other proteins are used as information pathways.

General Topics:

  • Topic 1: Water, the Solvent of Life
  • Topic 2: Amino Acids, Peptides, and Proteins
  • Topic 3: The Three-Dimensional Structure of Proteins
  • Topic 4: Protein Function
  • Topic 5: Enzymes
  • Topic 6: Carbohydrates and Glycobiology
  • Topic 7: Nucleotides and Nucleic Acids
  • Topic 8: Lipids
  • Topic 9: Biological Membranes and Transport
  • Topic 10: Biochemical Signaling
  • Topic 11: Introduction to Metabolism
  • Topic 12: Glycolysis, Gluconeogenesis, and the Pentose Phosphate Pathway
  • Topic 13: The Metabolism of Glycogen in Animals
  • Topic 14: The Citric Acid Cycle
  • Topic 15: Fatty Acid Catabolism
  • Topic 16: Oxidative Phosphorylation
  • Topic 17: Lipid Biosynthesis
  • Topic 18: Hormonal Regulation and Integration of Mammalian Metabolism
  • Topic 19: Genes and Chromosomes
  • Topic 20: DNA Metabolism
  • Topic 21: RNA Metabolism
  • Topic 22: Protein Metabolism
  • Topic 23: Regulation of Gene Expression
  • Topic 24: Final Exam
Instruction & Assessment

Instructional Strategies:

  • Audio Visual Materials
  • Computer Based Training
  • Practical Exercises

Methods of Assessment:

  • Examinations
  • Quizzes

Minimum Passing Score:

70%
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