The course objective is to initiate the application of Human Anatomy and Physiology by having students complete at-home laboratory experiments, guided by online exploration activities, exercises, and evaluations. It is the first part of a two part series. The lab course places emphasis on organization and overview of the human body, chemical reactions, maintenance of the body, integration, regulatory mechanisms and the dynamics of support and motion. Specific topics covered include anatomical terminology, organization of the body, histology, cell biology, and tissues, the integumentary system, the skeletal system, joints, the muscular system, nervous system, neural integration, special senses and the autonomic nervous system.